CAS No: 54-64-8
Thimerosal is a highly effective and well-characterized organomercurial compound, primarily used as a preservative and antimicrobial agent. Its main function is to prevent bacterial and fungal contamination in multi-dose formulations, particularly in vaccines and biological products, thereby ensuring product sterility throughout its shelf life after initial use.
Key Features & Benefits:
Proven Efficacy at Low Concentrations: Exceptionally effective against a broad spectrum of bacteria and fungi at typical use concentrations of 0.001% to 0.01%.
Liquid State & Excellent Solubility: Supplied as a stable, ready-to-use solution, easily soluble in water, alcohol, and other solvents, simplifying manufacturing processes.
Compatibility with Biologicals: Extensive historical use has demonstrated its compatibility with a wide range of antigens, antibodies, and sensitive biological materials without significantly compromising their potency or activity.
Critical for Multi-Dose Vials: Essential for maintaining the sterility of life-saving vaccines and injectables packaged in multi-dose vials, which are crucial for large-scale immunization programs in both developed and developing countries due to their cost-effectiveness and logistical advantages.
Primary Applications:
Thimerosal is a critical component in the manufacturing of:
Multi-Dose Vaccines: Used as a preservative in multi-dose vials of influenza, tetanus, diphtheria, and other vaccines, as recommended by WHO and other health agencies for global immunization programs;
Biological Products: Preservative for allergenic extracts, antisera, and other injectable biologicals supplied in multi-dose containers;
In-Vitro Diagnostic (IVD) Reagents: Used as an antimicrobial agent in diagnostic kit reagents, control solutions, and staining solutions to ensure longevity and reliability;
Ophthalmic & Nasal Solutions: Historically used in some contact lens solutions and nasal sprays (use in these applications has declined in many consumer markets).
Packing: 1 kg/Bottle, 25 kg/barrel
