CAS No.: 93106-60-6
EINECS No.: 618-911-2
Molecular Formula: C₁₉H₂₂FN₃O₃
Chemical Class: Synthetic fluoroquinolone antibacterial (veterinary use only)
Enrofloxacin is a concentration-dependent, bactericidal fluoroquinolone. It inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, blocking DNA replication, transcription and repair. In vivo it is partly metabolized to ciprofloxacin, contributing additional antibacterial activity.
Antimicrobial Spectrum
Active against:
Gram-negative: Escherichia coli, Salmonella, Pasteurella spp., Mannheimia haemolytica, Klebsiella, Actinobacillus pleuropneumoniae
Gram-positive: Staphylococcus spp.
Mycoplasma spp.
Limited/weak activity: Streptococcus spp., anaerobes; Pseudomonas may require higher exposure.
Target Species & Indications
Cattle / calves: respiratory disease (Pasteurella/Mannheimia/Mycoplasma), colibacillosis, septicaemia
Pigs: swine respiratory disease, colibacillosis, septicaemia
Poultry / livestock: respiratory, enteric and systemic bacterial infections (per regional registration)
Dogs & cats: skin/soft-tissue, UTI, respiratory, wound, otitis, GI infections
Aquaculture: bacterial septicemia, vibriosis, aeromoniasis (formulation-dependent)
Exotic / small mammals / birds / reptiles: per veterinary prescription
Typical Formulation Forms
Oral solution / soluble powder, tablets/capsules, injection (IV/SC/IM), premix / medicated feed, oral paste/suspension.
GMP & DMF approved
